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DRUG INTERACTIONS:


EVERYONE should consult with an appropriate health care practitioner before taking ivermectin.

People who consume any of the medications listed below should be extra careful and take special precautions as these drugs are believed to interact with ivermectin. ​


The list below is NOT meant to be a complete list. It is simply a quick guide to alert those who take any of these medications to be extra careful.


ALCOHOL - do NOT drink alcohol in combination with ivermectin.


Analgesics   Metamizole


Antibacterials  Clarithromycin  Rifabutin  Rifampicin  Rifapentine  Telithromycin


Antiarrhythmics  Quinidine


Anti-coagulant, Anti-platelet and Fibrinolytic  Acenocoumarol  Argatroban  Dipyridamole  Fondaparinux  Heparin  Phenprocoumon  Warfarin


Antidepressants  St. John’s wort


Anticonvulsants   Carbamazepine  Eslicarbazepine  Oxcarbazepine  Phenobarbital (Phenobarbitone)  Phenytoin  Primidone  Rufinamide


Antifungals   Griseofulvin  Itraconazole  Ketoconazole


Antipsychotics/Neuroleptics   Thioridazine ​


Calcium Channel Blockers  Verapamil


HCV DAAs  Glecaprevir/Pibrentasvir  Ombitasvir/Paritaprevir/r  Ombitasvir/Paritaprevir/r + Dasabuvir


HIV Antiretroviral Therapies  Atazanavir + ritonavir  Atazanavir/cobicistat  Efavirenz  Elvitegravir/Cobi/Emtricitabine/TAF  Elvitegravir/Cobi/Emtricitabine/TDF  Etravirine  Nevirapine


Covid-19 Antiviral Therapies  Atazanavir  Chloroquine  Hydroxychloroquine  Lopinavir/ritonavir


Covid-19 Immune Therapies  Ruxolitinib


Hypertension / Heart Failure Agents  Bosentan  Ranolazine


Immunosuppressants  Ciclosporin


Steroids  Betamethasone ​ ​


The above list was obtained from Covid19-DrugInteractions.org.

Click on the button below for additional information.

CONTRA-INDICATIONS AND DRUG INTERACTIONS

  

Additional caution should also be exercised with patients who are currently taking CYP 3A4 or P-gp inhibitor drugs such as:

Amiodarone

Clarithromycin

Cobicistat

Cyclosporine

Diltiazem

Erythromycin

Indinavir

Itraconazole

Ketoconazole

Quinidine

Ritonavir

Spironolactone,

Tacrolimus

Verapamil


SOURCE: ​https://clinicaltrials.gov/ct2/show/NCT04530474



EFFECTS OF EXTREME OVERUSE/ABUSE

NOTE: ​Even after serious overuse/abuse of ivermectin, the symptoms subsided after the patients stopped abusing the medication.

 

https://go.drugbank.com/drugs/DB00602?fbclid=IwAR3a6hnPiqLpdSuEkHwcuFHwGNPHXp-lIsw6Gi8G-XIS7Qiy1pxgUQ6nQuU


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